Human DsbA Recombinant Protein (RPPB1586)
- SKU:
- RPPB1586
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P0AEG4
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human DsbA Recombinant Protein |
| Product Code: | RPPB1586 |
| Size: | 50µg |
| Species: | Human |
| Target: | DsbA |
| Synonyms: | Disulfide oxidoreductase A, dsbA, rpbB, Disulfide oxidoreductase (DsbA) E Coli, DsDNA-binding protein A, Doublestranded DNA-binding protein, Disulfide oxidoreductase A periplasmic protein disulfide isomerase I, Thiol disulfide interchange protein dsbA. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | DsbA Human protein (1mg/ml) is formulated in 20mM Tris-HCl buffer (pH 7.5) and 2mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MAQYEDGKQY TTLEKPVAGA PQVLEFFSFF CPHCYQFEEV LHISDNVKKK LPEGVKMTKY HVNFMGGDLG KDLTQAWAVA MALGVEDKVT VPLFEGVQKT QTIRSASDIR DVFINAGIKG EEYDAAWNSF VVKSLVAQQE KAAADVQLRG VPAMFVNGKY QLNPQGMDTS NMDVFVQQYA DTVKYLSEKK |
Disulfide Oxidoreductase or DsbA is a protein, found in the plasma. It is part of the thioredoxin protein family. The protein creates disulfide bonds in the target proteins by contributing disulfide bond from its Cys30-Pro31-His32-Cys33 active site to a couple of cysteine residues.
DsbA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids (20-208) and having a molecular mass of 21.2 kDa.�DsbA Humanis purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. |
| UniProt Protein Details: | |
| NCBI Summary: | DsbA has a role in cytochrome C synthesis. [More information is available at EcoGene: EG11297]. |
| UniProt Code: | P0AEG4 |
| NCBI GenInfo Identifier: | 16131701 |
| NCBI Gene ID: | 948353 |
| NCBI Accession: | NP_418297.1 |
| UniProt Secondary Accession: | P0AEG4,P24991, Q2M8F8, Q46951, Q46952 |
| UniProt Related Accession: | P0AEG4 |
| Molecular Weight: | 23,105 Da |
| NCBI Full Name: | periplasmic protein disulfide isomerase I |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | dsbA�� |
| NCBI Official Synonym Symbols: | dsf; ECK3852; iarA; JW3832; ppfA�� |
| NCBI Protein Information: | periplasmic protein disulfide isomerase I |
| UniProt Protein Name: | Thiol:disulfide interchange protein DsbA |
| UniProt Synonym Protein Names: | |
| Protein Family: | Double-stranded DNA-binding protein |
| UniProt Gene Name: | dsbA�� |
| UniProt Entry Name: | DSBA_ECOLI |
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