Description
Human DST/Dystonin Recombinant Protein (N-His)
Human DST/Dystonin Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys580-Glu803, with an N-terminal His tag. Predicted molecular weight: 28.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dystonin (DST) is a ~860 kDa protein. Cytoskeletal linker protein. For research use only.
Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
| Product Name: | Human DST/Dystonin Recombinant Protein (N-His) |
| SKU: | GXRP07607 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Dystonin, 230 kDa bullous pemphigoid antigen, 230/240 kDa bullous pemphigoid antigen, Bullous pemphigoid antigen 1, BPA, Bullous pemphigoid antigen, Dystonia musculorum protein, Hemidesmosomal plaque protein, DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys580-Glu803 |
| Calculated MW: | 28.97 kDa |
| UniProt: | Q03001 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
