Description
Human DUT Recombinant Protein (N-His)
Human DUT Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met112-Asn252, with an N-terminal His tag. Predicted molecular weight: 17.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) is a ~26 kDa protein. Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis. For research use only.
Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor. Essential for embryonic development.
| Product Name: | Human DUT Recombinant Protein (N-His) |
| SKU: | GXRP05679 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | dUTP pyrophosphatase, DUT, dUTPase, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met112-Asn252 |
| Calculated MW: | 17.56 kDa |
| UniProt: | P33316 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
