Description
Human EBF1 Recombinant Protein (N-His)
Human EBF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp179-Ser451, with an N-terminal His tag. Predicted molecular weight: 32.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor COE1 (EBF1) is a ~64 kDa protein. Key pioneer transcription factor of B-cell specification and commitment. For research use only.
Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold.
| Product Name: | Human EBF1 Recombinant Protein (N-His) |
| SKU: | GXRP03019 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EBF, EBF1, OE-1, COE1, Early B-cell factor, Transcription factor COE1, O/E-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp179-Ser451 |
| Calculated MW: | 32.54 kDa |
| UniProt: | Q9UH73 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
