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Human ECT2 Recombinant Protein (N-His)
Key Features

Human ECT2 Recombinant Protein (N-His) (GXRP02872)

SKU GXRP02872
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ECT2 Recombinant Protein (N-His)

Human ECT2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe166-Gly348, with an N-terminal His tag. Predicted molecular weight: 23.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein ECT2 is a ~103 kDa protein. Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP. For research use only.

Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC, RAC1 and CDC42. Required for signal transduction pathways involved in the regulation of cytokinesis. Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Regulates the translocation of RHOA from the central spindle to the equatorial region.

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