Description
Human EDEM1 Recombinant Protein (N-His)
Human EDEM1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln125-Asp587, with an N-terminal His tag. Predicted molecular weight: 54.72 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ER degradation-enhancing alpha-mannosidase-like protein 1 is a ~73 kDa protein. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. For research use only.
It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
| Product Name: | Human EDEM1 Recombinant Protein (N-His) |
| SKU: | GXRP10973 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EDEM, EDEM1, ER degradation-enhancing alpha-mannosidase-like protein 1, KIAA0212 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln125-Asp587 |
| Calculated MW: | 54.72 kDa |
| UniProt: | Q92611 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
