Description
Human EGR2 Recombinant Protein (N-His)
Human EGR2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly147-Cys403, with an N-terminal His tag. Predicted molecular weight: 29.9 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 SUMO-protein ligase EGR2 is a ~50 kDa protein. Sequence-specific DNA-binding transcription factor. For research use only.
Plays a role in hindbrain segmentation by regulating the expression of a subset of homeobox containing genes and in Schwann cell myelination by regulating the expression of genes involved in the formation and maintenance of myelin. Binds to two EGR2-consensus sites EGR2A (5'-CTGTAGGAG-3') and EGR2B (5'-ATGTAGGTG-3') in the HOXB3 enhancer and promotes HOXB3 transcriptional activation. Binds to specific DNA sites located in the promoter region of HOXA4, HOXB2 and ERBB2. Regulates hindbrain segmentation by controlling the expression of Hox genes, such as HOXA4, HOXB3 and HOXB2, and thereby specifying odd and even rhombomeres.
| Product Name: | Human EGR2 Recombinant Protein (N-His) |
| SKU: | GXRP00864 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EGR-2, E3 SUMO-protein transferase ERG2, E3 SUMO-protein ligase EGR2, EGR2, Zinc finger protein Krox-20, AT591, Early growth response protein 2, KROX20 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly147-Cys403 |
| Calculated MW: | 29.9 kDa |
| UniProt: | P11161 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
