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Human ELOB Recombinant Protein (N-His)
Key Features

Human ELOB Recombinant Protein (N-His) (GXRP11515)

SKU GXRP11515
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ELOB Recombinant Protein (N-His)

Human ELOB Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gln118, with an N-terminal His tag. Predicted molecular weight: 15.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Elongin-B is a ~13 kDa protein. SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. For research use only.

Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells.

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