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Human EMD Recombinant Protein (N-His)
Key Features

Human EMD Recombinant Protein (N-His) (GXRP01721)

SKU GXRP01721
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human EMD Recombinant Protein (N-His)

Human EMD Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser66-Asn252, with an N-terminal His tag. Predicted molecular weight: 23.56 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Emerin (EMD) is a ~28 kDa protein. Stabilizes and promotes the formation of a nuclear actin cortical network. For research use only.

Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association.

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