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Human ENTPD5 Recombinant Protein (N-His)
Key Features

Human ENTPD5 Recombinant Protein (N-His) (GXRP07412)

SKU GXRP07412
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ENTPD5 Recombinant Protein (N-His)

Human ENTPD5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn25-His428, with an N-terminal His tag. Predicted molecular weight: 47.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nucleoside diphosphate phosphatase ENTPD5 is a ~47 kDa protein. Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. For research use only.

In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER.

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