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Human ERCC6 Recombinant Protein (N-His)
Key Features

Human ERCC6 Recombinant Protein (N-His) (GXRP13689)

SKU GXRP13689
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human ERCC6 Recombinant Protein (N-His)

Human ERCC6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val606-Gly996, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Chimeric ERCC6-PGBD3 protein is a ~119 kDa protein. Involved in repair of DNA damage following UV irradiation, acting either in the absence of ERCC6 or synergistically with ERCC6. For research use only.

Involved in the regulation of gene expression. In the absence of ERCC6, induces the expression of genes characteristic of interferon-like antiviral responses. This response is almost completely suppressed in the presence of ERCC6. In the presence of ERCC6, regulates the expression of genes involved in metabolism regulation, including IGFBP5 and IGFBP7.

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