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Human ERLIN1 Recombinant Protein (N-His)
Key Features

Human ERLIN1 Recombinant Protein (N-His) (GXRP05083)

SKU GXRP05083
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human ERLIN1 Recombinant Protein (N-His)

Human ERLIN1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu29-Thr173, with an N-terminal His tag. Predicted molecular weight: 18.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Erlin-1 (ERLIN1) is a ~39 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). For research use only.

Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.

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