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Human F7 (12D10-Fab) Antibody
Key Features

Human F7 (12D10-Fab) Antibody (GXBS02731)

SKU GXBS02731
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Chimeric
Reactivity Human
Applications ELISA, FCM, Functional assay, Research in vivo
Clone ID 12D10-Fab
Isotype Fab-nd-nd
€467 - €1,489

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Description

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Human F7 (12D10-Fab) Antibody

Human F7 (12D10-Fab) Antibody is a research-grade biosimilar monoclonal antibody targeting F7. Format: Fab-nd-nd (chimeric host). Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

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