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Human FA2H Recombinant Protein (N-His-SUMO)
Key Features

Human FA2H Recombinant Protein (N-His-SUMO) (GXRP04528)

SKU GXRP04528
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His-SUMO
$458 - $2,412

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Description

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Human FA2H Recombinant Protein (N-His-SUMO)

Human FA2H Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Ser12-Arg86, with an N-terminal His-SUMO tag. Predicted molecular weight: 20.86 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fatty acid 2-hydroxylase (FA2H) is a ~42 kDa protein. Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. For research use only.

FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis.

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