Description
Human FBP1 Recombinant Protein (N-His)
Human FBP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gln338, with an N-terminal His tag. Predicted molecular weight: 39 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fructose-1,6-bisphosphatase 1 (FBP1) is a ~36 kDa protein. Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. For research use only.
Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
| Product Name: | Human FBP1 Recombinant Protein (N-His) |
| SKU: | GXRP00777 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | FBPase 1, FBP1, Liver FBPase, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, FBP, Fructose-1, 6-bisphosphatase 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Gln338 |
| Calculated MW: | 39 kDa |
| UniProt: | P09467 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
