Description
Human FBXO2 Recombinant Protein (N-His)
Human FBXO2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Pro296, with an N-terminal His tag. Predicted molecular weight: 35.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. F-box only protein 2 (FBXO2) is a ~33 kDa protein. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. For research use only.
Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
| Product Name: | Human FBXO2 Recombinant Protein (N-His) |
| SKU: | GXRP03238 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | F-box only protein 2, FBX2, FBXO2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Pro296 |
| Calculated MW: | 35.49 kDa |
| UniProt: | Q9UK22 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
