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Human FER Recombinant Protein (N-His)
Key Features

Human FER Recombinant Protein (N-His) (GXRP11280)

SKU GXRP11280
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human FER Recombinant Protein (N-His)

Human FER Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser451-Thr822, with an N-terminal His tag. Predicted molecular weight: 44.96 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tyrosine-protein kinase Fer is a ~94 kDa protein. Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. For research use only.

Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase.

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