Description
Human FERMT2 Recombinant Protein (N-His-SUMO & C-Strep)
Human FERMT2 Recombinant Protein (N-His-SUMO & C-Strep) is a recombinant protein expressed in E. coli, spanning Pro373-Lys497, with an N-terminal His-SUMO tag and a C-terminal Strep tag. Predicted molecular weight: 27.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fermitin family homolog 2 (FERMT2) is a ~77 kDa protein. Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. For research use only.
Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation.
| Product Name: | Human FERMT2 Recombinant Protein (N-His-SUMO & C-Strep) |
| SKU: | GXRP04182 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PLEKHC1, Mitogen-inducible gene 2 protein, Pleckstrin homology domain-containing family C member 1, Fermitin family homolog 2, PH domain-containing family C member 1, MIG-2, KIND2, FERMT2, MIG2, Kindlin-2 |
| Tag: | N-His-SUMO & C-Strep |
| Expression Host: | E. coli |
| Protein Length: | Pro373-Lys497 |
| Calculated MW: | 27.93 kDa |
| UniProt: | Q96AC1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
