Description
Human FOXA3 Recombinant Protein (N-His)
Human FOXA3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu207, with an N-terminal His tag. Predicted molecular weight: 24.52 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Hepatocyte nuclear factor 3-gamma (FOXA3) is a ~37 kDa protein. Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. For research use only.
Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC1 promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA.
| Product Name: | Human FOXA3 Recombinant Protein (N-His) |
| SKU: | GXRP01841 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TCF-3G, TCF3G, Fork head-related protein FKH H3, HNF-3-gamma, HNF-3G, HNF3G, FOXA3, Hepatocyte nuclear factor 3-gamma, Forkhead box protein A3, Transcription factor 3G |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu207 |
| Calculated MW: | 24.52 kDa |
| UniProt: | P55318 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
