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Human FOXL2 Recombinant Protein (N-GST & C-His)
Key Features

Human FOXL2 Recombinant Protein (N-GST & C-His) (GXRP13608)

SKU GXRP13608
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-GST & C-His
$458 - $2,412

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Description

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Human FOXL2 Recombinant Protein (N-GST & C-His)

Human FOXL2 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Ser58-Gly141, with an N-terminal GST tag and a C-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Forkhead box protein L2 is a ~38 kDa protein. Transcriptional regulator. For research use only.

Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen.

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