Description
Human FOXO1 Recombinant Protein (N-His)
Human FOXO1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser301-Gly655, with an N-terminal His tag. Predicted molecular weight: 40.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Forkhead box protein O1 (FOXO1) is a ~69 kDa protein. Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. For research use only.
Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism.
| Product Name: | Human FOXO1 Recombinant Protein (N-His) |
| SKU: | GXRP02121 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Forkhead box protein O1, FKHR, FOXO1A, Forkhead in rhabdomyosarcoma, Forkhead box protein O1A, FOXO1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser301-Gly655 |
| Calculated MW: | 40.81 kDa |
| UniProt: | Q12778 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
