Description
Human FRK Recombinant Protein (N-His)
Human FRK Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile234-Phe491, with an N-terminal His tag. Predicted molecular weight: 32.16 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tyrosine-protein kinase FRK is a ~58 kDa protein. Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. For research use only.
Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
| Product Name: | Human FRK Recombinant Protein (N-His) |
| SKU: | GXRP01591 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PTK5, RAK, Tyrosine-protein kinase FRK, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, FYN-related kinase, FRK |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile234-Phe491 |
| Calculated MW: | 32.16 kDa |
| UniProt: | P42685 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
