Description
Human FRS2 Recombinant Protein (N-His)
Human FRS2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys7-Met508, with an N-terminal His tag. Predicted molecular weight: 58.75 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fibroblast growth factor receptor substrate 2 (FRS2) is a ~57 kDa protein. Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. For research use only.
Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
| Product Name: | Human FRS2 Recombinant Protein (N-His) |
| SKU: | GXRP08041 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | FGFR substrate 2, FRS2, Fibroblast growth factor receptor substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Cys7-Met508 |
| Calculated MW: | 58.75 kDa |
| UniProt: | Q8WU20 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
