Human FZD4 Full-Length Bioactive Membrane Protein (HDFP120)
- SKU:
- HDFP120
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- Q9ULV1
Frequently bought together:
Description
system_update_altDatasheet
| Product name | Human FZD4 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP120 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | FZD4 |
| Uniprot: | Q9ULV1 |
| Description: | Human FZD4 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length FZD4 protein has a MW of 60.3 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | A member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |
| Delivery: | In Stock |
| Usage | Research use only |
