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Human GDNF Recombinant Protein (N-His)
Key Features

Human GDNF Recombinant Protein (N-His) (GXRP01541)

SKU GXRP01541
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human GDNF Recombinant Protein (N-His)

Human GDNF Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser78-Ile211, with an N-terminal His tag. Predicted molecular weight: 17.36 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. For research use only.

Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.

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