Description
Human GET3 Recombinant Protein (N-His)
Human GET3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser36-Gln348, with an N-terminal His tag. Predicted molecular weight: 37.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATPase GET3 is a ~38 kDa protein. ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. For research use only.
Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.
| Product Name: | Human GET3 Recombinant Protein (N-His) |
| SKU: | GXRP05079 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Arsenite-stimulated ATPase, TRC40, ATPase GET3, hASNA-I, Arsenical pump-driving ATPase, hARSA-I, GET3, ARSA, ASNA1, Guided entry of tail-anchored proteins factor 3, ATPase, Transmembrane domain recognition complex 40 kDa ATPase subunit |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser36-Gln348 |
| Calculated MW: | 37.33 kDa |
| UniProt: | O43681 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
