Description
Human GLDN Recombinant Protein (N-His)
Human GLDN Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met303-Gln551, with an N-terminal His tag. Predicted molecular weight: 30.65 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Gliomedin is a ~58 kDa protein. Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. For research use only.
Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters.
| Product Name: | Human GLDN Recombinant Protein (N-His) |
| SKU: | GXRP11641 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | COLM, GLDN, Gliomedin, Gliomedin shedded ectodomain |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met303-Gln551 |
| Calculated MW: | 30.65 kDa |
| UniProt: | Q6ZMI3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
