Description
Human GNA15 Recombinant Protein (N-His)
Human GNA15 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu42-Leu374, with an N-terminal His tag. Predicted molecular weight: 40.96 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Guanine nucleotide-binding protein subunit alpha-15 is a ~43 kDa protein. Member of the G-protein alpha subunit family that plays a crucial role in intracellular signaling. For research use only.
Functions as a molecular switch, transducing signals from G protein-coupled receptors (GPCRs) to downstream effectors. In collaboration with the adapter protein TTC1, promotes HRAS activation and ERK1/2 phosphorylation independently of phospholipase Cbeta signaling. Also initiates EMR2-mediated signaling, leading to activation of Akt, MAPK, and NF-kappa-B, which in turn drives macrophage differentiation and inflammatory responses.
| Product Name: | Human GNA15 Recombinant Protein (N-His) |
| SKU: | GXRP11199 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Epididymis tissue protein Li 17E, G alpha-15, G alpha-16, G-protein subunit alpha-15, G-protein subunit alpha-16, GNA15, GNA16, Guanine nucleotide-binding protein subunit alpha-15, Guanine nucleotide-binding protein subunit alpha-16 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu42-Leu374 |
| Calculated MW: | 40.96 kDa |
| UniProt: | P30679 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
