Description
Human GNPDA1 Recombinant Protein (N-His)
Human GNPDA1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp289, with an N-terminal His tag. Predicted molecular weight: 34.83 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glucosamine-6-phosphate deaminase 1 (GNPDA1) is a ~32 kDa protein. Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. For research use only.
Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling. Seems to trigger calcium oscillations in mammalian eggs.
| Product Name: | Human GNPDA1 Recombinant Protein (N-His) |
| SKU: | GXRP06314 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | GNPDA1, GlcN6P deaminase 1, Glucosamine-6-phosphate deaminase 1, GNPI, GNPDA 1, Oscillin, KIAA0060, HLN, Glucosamine-6-phosphate isomerase 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asp289 |
| Calculated MW: | 34.83 kDa |
| UniProt: | P46926 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
