Description
Human GP2 Recombinant Protein (N-His)
Human GP2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe307-Asn512, with an N-terminal His tag. Predicted molecular weight: 25.36 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Pancreatic secretory granule membrane major glycoprotein GP2 is a ~59 kDa protein. Functions as an intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. For research use only.
At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response.
| Product Name: | Human GP2 Recombinant Protein (N-His) |
| SKU: | GXRP01833 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Pancreatic zymogen granule membrane protein GP-2, GP2, ZAP75, Pancreatic secretory granule membrane major glycoprotein GP2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe307-Asn512 |
| Calculated MW: | 25.36 kDa |
| UniProt: | P55259 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
