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Human GP6 Recombinant Protein (N-His)
Key Features

Human GP6 Recombinant Protein (N-His) (GXRP02893)

SKU GXRP02893
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human GP6 Recombinant Protein (N-His)

Human GP6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Tyr86-Thr231, with an N-terminal His tag. Predicted molecular weight: 18.2 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Platelet glycoprotein VI (GP6/GPVI) is a ~36 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. For research use only.

Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.

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