Description
Human GRB14 Recombinant Protein (N-His)
Human GRB14 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg105-Leu540, with an N-terminal His tag. Predicted molecular weight: 52.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Growth factor receptor-bound protein 14 is a ~60 kDa protein. Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. For research use only.
Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
| Product Name: | Human GRB14 Recombinant Protein (N-His) |
| SKU: | GXRP09320 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg105-Leu540 |
| Calculated MW: | 52.43 kDa |
| UniProt: | Q14449 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
