Description
Human GRHL2 Recombinant Protein (N-His)
Human GRHL2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln274-Cys417, with an N-terminal His tag. Predicted molecular weight: 19.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Grainyhead-like protein 2 homolog is a ~71 kDa protein. Transcription factor playing an important role in primary neurulation and in epithelial development. For research use only.
Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes. During embryogenesis, plays unique and cooperative roles with GRHL3 in establishing distinct zones of primary neurulation. Essential for closure 3 (rostral end of the forebrain), functions cooperatively with GRHL3 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure. Regulates epithelial morphogenesis acting as a target gene-associated transcriptional activator of apical junctional complex components.
| Product Name: | Human GRHL2 Recombinant Protein (N-His) |
| SKU: | GXRP11604 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BOM, Brother of mammalian grainyhead, GRHL2, Grainyhead-like protein 2 homolog, TFCP2L3, Transcription factor CP2-like 3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln274-Cys417 |
| Calculated MW: | 19.20 kDa |
| UniProt: | Q6ISB3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
