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Human H2AB1 Recombinant Protein (C-His)
Key Features

Human H2AB1 Recombinant Protein (C-His) (GXRP07531)

SKU GXRP07531
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag C-His
€347 - €1,827

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Description

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Human H2AB1 Recombinant Protein (C-His)

Human H2AB1 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp115, with a C-terminal His tag. Predicted molecular weight: 13.76 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Histone H2A-Bbd type 1 (H2AB1) is a ~12 kDa protein. Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. For research use only.

Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase.

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