Description
Human HAND2 Recombinant Protein (N-His-KSI)
Human HAND2 Recombinant Protein (N-His-KSI) is a recombinant protein expressed in E. coli, spanning Ser2-Gln217, with an N-terminal His-KSI tag. Predicted molecular weight: 39.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Heart- and neural crest derivatives-expressed protein 2 is a ~23 kDa protein. Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. For research use only.
Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
| Product Name: | Human HAND2 Recombinant Protein (N-His-KSI) |
| SKU: | GXRP08830 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum heart autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, HAND2 |
| Tag: | N-His-KSI |
| Expression Host: | E. coli |
| Protein Length: | Ser2-Gln217 |
| Calculated MW: | 39.30 kDa |
| UniProt: | P61296 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
