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Human HAT1 Recombinant Protein (N-His)
Key Features

Human HAT1 Recombinant Protein (N-His) (GXRP11720)

SKU GXRP11720
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human HAT1 Recombinant Protein (N-His)

Human HAT1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu419, with an N-terminal His tag. Predicted molecular weight: 51.68 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Histone acetyltransferase type B catalytic subunit is a ~49 kDa protein. Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. For research use only.

Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac). Drives H4 production by chromatin binding to support chromatin replication and acetylation. Since transcription of H4 genes is tightly coupled to S-phase, plays an important role in S-phase entry and progression.

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