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Human HEMK2 Recombinant Protein (C-His)
Key Features

Human HEMK2 Recombinant Protein (C-His) (GXRP13666)

SKU GXRP13666
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag C-His
$458 - $2,412

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Description

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Human HEMK2 Recombinant Protein (C-His)

Human HEMK2 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser214, with a C-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Methyltransferase HEMK2 is a ~22 kDa protein. Methyltransferase that can methylate proteins and, to a lower extent, arsenic. For research use only.

Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid.

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