Description
Human HORMAD1 Recombinant Protein (N-His)
Human HORMAD1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser21-Arg232, with an N-terminal His tag. Predicted molecular weight: 26.60 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. HORMA domain-containing protein 1 (HORMAD1) is a ~45 kDa protein. Plays a key role in meiotic progression. For research use only.
Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
| Product Name: | Human HORMAD1 Recombinant Protein (N-His) |
| SKU: | GXRP05099 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cancer/testis antigen 46, CT46, HORMA domain-containing protein 1, NOHMA, Newborn ovary HORMA protein, HORMAD1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser21-Arg232 |
| Calculated MW: | 26.60 kDa |
| UniProt: | Q86X24 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
