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Human HPS1 Recombinant Protein (N-His)
Key Features

Human HPS1 Recombinant Protein (N-His) (GXRP13657)

SKU GXRP13657
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human HPS1 Recombinant Protein (N-His)

Human HPS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Thr489, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. BLOC-3 complex member HPS1 is a ~79 kDa protein. Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. For research use only.

The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.

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