Description
Human HPS6 Recombinant Protein (N-His)
Human HPS6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr6-Gly387, with an N-terminal His tag. Predicted molecular weight: 42.44 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. BLOC-2 complex member HPS6 is a ~82 kDa protein. May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. For research use only.
Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning.
| Product Name: | Human HPS6 Recombinant Protein (N-His) |
| SKU: | GXRP12041 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BLOC-2 complex member HPS6, HPS6, Hermansky-Pudlak syndrome 6 protein, Ru, Ruby-eye protein homolog |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr6-Gly387 |
| Calculated MW: | 42.44 kDa |
| UniProt: | Q86YV9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
