Description
Human HSPA9 Recombinant Protein (N-His)
Human HSPA9 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser65-Ala311, with an N-terminal His tag. Predicted molecular weight: 29.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Stress-70 protein, mitochondrial (HSPA9/Mortalin) is a ~73 kDa protein. Mitochondrial chaperone that plays a key role in mitochondrial protein import, folding, and assembly. For research use only.
Plays an essential role in the protein quality control system, the correct folding of proteins, the re-folding of misfolded proteins, and the targeting of proteins for subsequent degradation. These processes are achieved through cycles of ATP binding, ATP hydrolysis, and ADP release, mediated by co-chaperones. In mitochondria, it associates with the TIM (translocase of the inner membrane) protein complex to assist in the import and folding of mitochondrial proteins. Plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis, interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU.
| Product Name: | Human HSPA9 Recombinant Protein (N-His) |
| SKU: | GXRP01534 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | mt-HSP70, HSPA9B, MOT, Peptide-binding protein 74, Stress-70 protein, mitochondrial, PBP74, GRP-75, Mortalin, Heat shock 70 kDa protein 9, GRP75, 75 kDa glucose-regulated protein, HSPA9 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser65-Ala311 |
| Calculated MW: | 29.35 kDa |
| UniProt: | P38646 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
