Description
Human HSPB11 Recombinant Protein (N-His)
Human HSPB11 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser144, with an N-terminal His tag. Predicted molecular weight: 18.46 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Intraflagellar transport protein 25 homolog is a ~16 kDa protein. Component of the IFT complex B required for sonic hedgehog/SHH signaling. For research use only.
May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation.
| Product Name: | Human HSPB11 Recombinant Protein (N-His) |
| SKU: | GXRP08656 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Intraflagellar transport protein 25 homolog, Heat shock protein beta-11, Hspb11, Placental protein 25, PP25, HSPB11, C1orf41, IFT25, HSPC034 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ser144 |
| Calculated MW: | 18.46 kDa |
| UniProt: | Q9Y547 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
