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Human ICAM3 Recombinant Protein (N-His)
Key Features

Human ICAM3 Recombinant Protein (N-His) (GXRP13582)

SKU GXRP13582
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human ICAM3 Recombinant Protein (N-His)

Human ICAM3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg224-Glu480, with an N-terminal His tag. Predicted molecular weight: 30.23 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Intercellular adhesion molecule 3 is a ~59 kDa protein. Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring apoptotic neutrophil phagocytosis by macrophages. For research use only.

Is also a ligand for integrin ITGAD/ITGB2. Ligand of CD209 on dendritic cells (DC) through an integrin-independent mechanism that requires Ca(2+) and that forms a first contact between DC and resting T cell, facilitating the downstream DC-T cell clustering process and DC-induced proliferation of resting T Cells.

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