Description
Human ID3 Recombinant Protein (N-His)
Human ID3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-His119, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA-binding protein inhibitor ID-3 is a ~12 kDa protein. Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. For research use only.
Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.
| Product Name: | Human ID3 Recombinant Protein (N-His) |
| SKU: | GXRP13603 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 1R21, BHLHB25, Class B basic helix-loop-helix protein 25, DNA-binding protein inhibitor ID-3, HEIR1, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21, ID3, Inhibitor of DNA binding 3, Inhibitor of differentiation 3, bHLHb25 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-His119 |
| UniProt: | Q02535 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |