Description
Human IFIT5 Recombinant Protein (N-His)
Human IFIT5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ile482, with an N-terminal His tag. Predicted molecular weight: 58.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) is a ~55 kDa protein. Interferon-induced RNA-binding protein involved in the human innate immune response. For research use only.
Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments. Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection.
| Product Name: | Human IFIT5 Recombinant Protein (N-His) |
| SKU: | GXRP04890 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ISG58, RI58, IFIT-5, P58, Interferon-induced protein with tetratricopeptide repeats 5, IFIT5, Retinoic acid- and interferon-inducible 58 kDa protein, Interferon-induced 58 kDa protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ile482 |
| Calculated MW: | 58.01 kDa |
| UniProt: | Q13325 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
