Description
Human IGF2BP1 Recombinant Protein (N-His)
Human IGF2BP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val194-Asn369, with an N-terminal His tag. Predicted molecular weight: 21.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is a ~63 kDa protein. RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). For research use only.
This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons.
| Product Name: | Human IGF2BP1 Recombinant Protein (N-His) |
| SKU: | GXRP04265 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | VICKZ family member 1, Zipcode-binding protein 1, IGF2BP1, VICKZ1, Coding region determinant-binding protein, IMP1, IMP-1, ZBP1, IGF-II mRNA-binding protein 1, CRDBP, Insulin-like growth factor 2 mRNA-binding protein 1, ZBP-1, CRD-BP, IGF2 mRNA-binding protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val194-Asn369 |
| Calculated MW: | 21.71 kDa |
| UniProt: | Q9NZI8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
