Description
Human IKZF2 Recombinant Protein (N-His)
Human IKZF2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp92-Met227, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Zinc finger protein Helios is a ~59 kDa protein. Transcription factor, which stabilizes the noninflammatory phenotype of regulatory T cells (Tregs). For research use only.
May possibly act via STAT5-mediated signaling. Binds IL2 promoter and represses its transcription, possibly by epigenetic silencing, inducing deacetylation of core histones in the IL2 promoter. In Tregs, required for FOXP3 recruitment to the IL2 promoter. Required for outer hair cells maturation and, consequently, for hearing.
| Product Name: | Human IKZF2 Recombinant Protein (N-His) |
| SKU: | GXRP13635 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | HELIOS, IKZF2, Ikaros family zinc finger protein 2, ZNFN1A2, Zinc finger protein Helios |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp92-Met227 |
| UniProt: | Q9UKS7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
