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Human IL9 Recombinant Protein (C-His)
Key Features

Human IL9 Recombinant Protein (C-His) (GXRP01003)

SKU GXRP01003
Product Type Recombinant Protein
Species Human
Expression System Mammalian cells
Tag C-His
Purity >90% as determined by SDS-PAGE.
$577 - $4,138

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Description

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Human IL9 Recombinant Protein (C-His)

Human IL9 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Gln19-Ile144, with a C-terminal His tag. Predicted molecular weight: 16.88 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interleukin-9 (IL9) is a ~15 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. For research use only.

Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs.

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