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Human IMPDH2 Recombinant Protein (N-His)
Key Features

Human IMPDH2 Recombinant Protein (N-His) (GXRP00907)

SKU GXRP00907
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human IMPDH2 Recombinant Protein (N-His)

Human IMPDH2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp226-Phe514, with an N-terminal His tag. Predicted molecular weight: 33.4 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) is a ~55 kDa protein. Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. For research use only.

Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

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