Description
Human ISL1 Recombinant Protein (N-His)
Human ISL1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ala349, with an N-terminal His tag. Predicted molecular weight: 41.2 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Insulin gene enhancer protein ISL-1 (ISL1) is a ~39 kDa protein. DNA-binding transcriptional activator. For research use only.
Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1.
| Product Name: | Human ISL1 Recombinant Protein (N-His) |
| SKU: | GXRP01892 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Insulin gene enhancer protein ISL-1, ISL1, Islet-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ala349 |
| Calculated MW: | 41.2 kDa |
| UniProt: | P61371 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
